Pharmacological treatment of acute lymphoblastic leukaemia in paediatric patients

Abstract

Vincristine is the most optimal and the drug of choice in the treatment regimen of ALL in pediatric patients. Both Dexamethason and Prednisolone are used in the treatment of ALL, where one of them has a high therapeutic index while the other one is safer to use. A four-drug regimen is needed in case of high-risk ALL.