Comparison of different methods in sampling and sample preparation of Chlorpromazine from biological matrix

A tétel rövid nézete
dc.contributor.advisorBak, István Jr
dc.contributor.advisorBak, István Jr
dc.contributor.advisordeptDebreceni Egyetem::Gyógyszerésztudományi Kar::Gyógyszerhatástani Tanszékhu_HU
dc.contributor.authorNguyen, Thai Minh Hoang Jr
dc.contributor.authorNguyen, Thai Minh Hoang Jr
dc.contributor.departmentDE--Gyógyszerésztudományi Karhu_HU
dc.contributor.opponentKiss, Attila Jr
dc.contributor.opponentKiss, Attila Jr
dc.contributor.opponentdeptDebreceni Egyetem::Természettudományi és Technológiai Kar::Kémiai Intézethu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Természettudományi és Technológiai Kar::Kémiai Intézethu_HU
dc.date.accessioned2022-05-06T06:46:34Z
dc.date.available2022-05-06T06:46:34Z
dc.date.created2022
dc.description.abstractIn this thesis, the efficiency and operational aspects of 2 extraction methods, microextraction by packed sorbent (MEPS) and solid-phase microextraction (SPME), were compared by their performance in quantifying chlorpromazine (CPZ) concentration of rat plasma samples. The extracts were then be analyzed by GCMS. Unfortunately, the GCMS instrument had a technical dysfunction before the final experiments could be performed. Despite that, it is shown that although it required a more complicated method development, SPME has better accuracy when analyzing the CPZ content of the samples than MEPS. However, the study still needs further investigation for strengthening the findingshu_HU
dc.description.coursegyógyszerészhu_HU
dc.description.courselangangolhu_HU
dc.description.coursespecBioanalitikahu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent36hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/332500
dc.language.isoenhu_HU
dc.subjectMicroextraction by Packed Sorbent (MEPS), Solid-Phase Microextraction (SPME), Chlorpromazine.hu_HU
dc.subject.dspaceDEENK Témalista::Kémia::Analitikai kémiahu_HU
dc.titleComparison of different methods in sampling and sample preparation of Chlorpromazine from biological matrixhu_HU
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Gyűjtemények
Theses (Faculty of Pharmacy)