This thesis has thoroughly examined the complex aspects of sialolithiasis in salivary glands, including its biochemical composition, etiology, clinical manifestations, diagnostic methods, and theraputic options. Following a comprehensive review of current review of current literature and novel research, we have determined that sialolithiasis, is frequently underdiagnosed and poorly handled. Ultimately, improving our comprehension of sialolithiasis would not only refine clinical treatment but also augment the broaded domain of oral and maxillofacial health. Ongoing clinical collabaration and research is crucial for tackling the problems presented by this disorder and enhancing the quality of treatment for those affected.