Depression or MDD is a common but serious mental health disorder.Recent revival of psychedelic research has modelled the human brain in a number of different psychiatric pathologies and normal physiological processes but, more excitingly, has presented possible alternatives for treatments. The exclusive low-toxicity profile, lack of addictive potential, high tolerability and encouraging response rates, including in ‘treatment-resistant depression’ has contributed in the growing excitement of the highly efficacious serotonin receptor agonist, Psilocybin