Fatty acid oxidation inhibitor and its role in management of angina pectoris

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorAlakhras, Mohammad Adnan Mohammad
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptKenézy Kórház, Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.date.accessioned2021-09-17T08:41:33Z
dc.date.available2021-09-17T08:41:33Z
dc.date.created2021-08-04
dc.description.abstractFatty acid oxidation inhibitors showed in the recent researches the effect on controlling of many cardiac diseases and here I’m going to spot on the effect of the fatty acid oxidation inhibitors in the management of angina pectoris, since angina pectoris has an estimated prevalence of 4.6 million in women and 3.3 million in men. Fatty acid oxidation inhibitors can play their role and inhibit fatty acid oxidation in many different ways by example the direct inhibitors of fatty acid oxidation are Trimrtazidine and Ranolazine, drugs are working at the level of the carnitine palmitoyltransferase ( CPT-1) inhibitors by example Etomoxir, Oxfenicine and Perhexiline and other drugs working on inhibition of carnitine biosynthesis by example mildronate. Fatty acid oxidation inhibitors are doing their function by decreasing the amount of the oxygen required by decreasing the heart rate, contractility and due to that the cardiac work will be less. Fatty acid oxidation inhibitors also have an important vulnerable effect on angina patient with maximum dose of the other angina drugs by example calcium channel blocker or beta blocker but still symptomatic. Other than this those drugs are increasing the mechanical efficacy of the left ventricle without hemodynamic disturbances.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent43hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/321840
dc.language.isoenhu_HU
dc.subjectfatty acid oxidation inhibitorhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleFatty acid oxidation inhibitor and its role in management of angina pectorishu_HU
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