Allergic rhinitis is one of the most prevalent chronic inflammatory conditions in children and significantly affects overall quality of life. This thesis evaluates the comparative effectiveness and safety of oral antihistamines and leukotriene receptor blockers in the management of pediatric allergic rhinitis. A structured narrative review of randomised controlled trials and meta-analyses, including international guidelines, was conducted. The findings show antihistamines provide superior overall symptom control, particularly for daytime symptoms, while montelukast is more beneficial for nasal congestion and for children coexisting with asthma. Treatment selection should therefore be individualised based on symptom profile, safety considerations and current guidelines.