pharmacological treatment of osteomyelitis

A tétel rövid nézete
dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorAyoub, Abu Khadra
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentdeptKenézy Kórház, Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2021-06-18T09:50:36Z
dc.date.available2021-06-18T09:50:36Z
dc.date.created2020-08-12
dc.description.abstractAdministration of locally acting antibiotics is important as it allows the best availability of the drug. Besides the invasive measure that needs to take place it has been proven very effective in the treatment of osteomyelitis. Non-biodegradable carriers such as PMMA has been the gold standard go to method for years. It has revolutionized the treatment of chronic osteomyelitis. It provides mechanical stability of the bone while also simultaneously having an antimicrobial effect. Due to its non-absorbable property however, it is a problem to reopen the wound to remove the implanted material as the drug levels will eventually reach a suboptimal level. As a result pathogens can reside on the carrier and thrive to form new colonies and spread to the surrounding tissue. Moreover, such invasive intervention risks nosocomial infections and possible complications due to errors caused by the medical staff.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent37hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/311328
dc.language.isoenhu_HU
dc.subjectosteomyelitishu_HU
dc.subjectAntibiotic Impregnated Materialshu_HU
dc.subjectBiodegradable Implants
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titlepharmacological treatment of osteomyelitishu_HU
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