Pharmacological Modulation Of The Renin Angiotensin Aldosterone System

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDepartment Of Pharmacology And Pharmacotherapyhu_HU
dc.contributor.authorEmaiye, Oluwatoyin Igbekele Esther
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptKenézy Kórház, Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.date.accessioned2021-05-16T08:23:17Z
dc.date.available2021-05-16T08:23:17Z
dc.date.created2021-03-01
dc.description.abstractThe RAAS is a very important hormonal system that is responsible for the chronic control of blood pressure and fluid balance. The overall effect of RAAS activation is the elevation of arterial blood pressure which is mediated through vasoconstriction and increased sodium and water reabsorption in the renal tubules.Several conditions can lead to the wrongful activation of the RAAS, an example is the stenosis of the renal artery which will cause reduced blood flow to the kidney. In this setting the JGCs of the kidney senses the reduced perfusion and kickstarts the activation of the RAAS cascade. The pharmacological modulation of RAAS has been a subject of research for several years. Several medications have been developed to inhibit or modify the various components of this system at different levels. The most common groups of drugs used are the ACE inhibitors, ARBs, aldosterone antagonists and newer classes of drugs like direct renin inhibitors and other investigational drugs like : vasopeptidase inhibitors and dual neprilysin and angiotensin receptor inhibitors.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent41hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/309678
dc.language.isoenhu_HU
dc.subjectKidneyhu_HU
dc.subjectHypertensionhu_HU
dc.subjectrenin angiotensin aldosterone systemhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titlePharmacological Modulation Of The Renin Angiotensin Aldosterone Systemhu_HU
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