Clinical significance of adenosine receptor agonists

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Adenosine is a ubiquitous extracellular signaling molecule with essential functions in human physiology. Adenosine receptors have a widespread expression and extensive effects across different organs. With a noteworthy role in the cardiovascular system, they have been extensively studied for both their therapeutic and diagnostic abilities. 99% of Paroxysmal SVT involving the AV node are successfully terminated with standard doses of adenosine. Adenosine receptor agonist are divided into non-selective, A1, A2 and A3 ARA. The non- selective ARAs are adenosine, NECA and 2-Cl-Ado. The A1 ARA are CAPADENOSON, CCPA, etc. The A2 ARA are APADENOSON, BAY60-6583, BINODENOSON, etc. A3 ARAs are CF-101, CF-102, CF502.

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adenosine
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