Direct-acting antiviral in the treatment of hepatitis c virus: a review of pharmacology and clinical application

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorTrinh, GiaKhanh
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentdeptKenézy Kórház Aneszteziológiai és Intenziv Therápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2017-08-02T10:49:50Z
dc.date.available2017-08-02T10:49:50Z
dc.date.created2017-05
dc.description.abstractHCV is a global public health issue with millions people affected around the world. Chronic HCV infection can lead to severe long-term consequences like cirrhosis, liver cancer and liver failure. The treatment of choice before 2011 was PEG-Interferon with low effectiveness and many unwanted side effects. The approval of direct-acting antiviral therapy in 2011 has significantly changed the treatment effectiveness of chronic HCV infection. This thesis aims to provide a overview the molecular basis of Direct-acting Antiviral, the pharmacology of each group of the Direct-acting antiviral agents including their clinical applications, as well as the challenges they are facing.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent38hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/242816
dc.language.isoenhu_HU
dc.subjectDirect-acting antiviralhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudomány::Farmakológiahu_HU
dc.titleDirect-acting antiviral in the treatment of hepatitis c virus: a review of pharmacology and clinical applicationhu_HU
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Gyűjtemények
Theses (Faculty of Medicine)