The use of gabapentin in anesthesiological practice

Abstract

Gabapentin is a structural analogue of gamma amino butyric acid (GABA),As this carrier-dependent transport is saturable, the bioavailability of gabapentin varies inversely with dose.it is thought to exert its action by interaction with a receptor associated with the L-system amino acid carrier protein.. Gabapentin has proved to be efficacious as an adjunct to other anticonvulsants in the treatment of partial seizures and generalised tonic-clonic seizures in patients over 12 years of age