This thesis explores the dental management of patients undergoing allogeneic peripheral blood stem cell transplantation, focusing on how immunosuppression and intensive treatments like chemotherapy and total body irradiation impact oral health. It outlines the stages of transplantation and aligns dental care strategies with each phase to minimize complications such as oral mucositis, infections, and graft-versus-host disease. The study emphasizes the importance of early dental intervention, professional oral health care, and continuous monitoring. Overall, the thesis provides a thorough, evidence-based guide to improving oral outcomes and quality of life for allo-PBSCT patients.