Pseudodementia pathomechanism – neuropathological link between depression and dementia

Dátum
Szerzők
Elimelech, Elihanan Asher
Folyóirat címe
Folyóirat ISSN
Kötet címe (évfolyam száma)
Kiadó
Absztrakt
The relationship between depression and dementia is complex and still not well understood. A few putative pathological mechanisms leading to depression, cognitive dysfunction and dementia, were investigated, involving the: HPA axis and Glucocorticoid system, Serotonergic system, Glutamatergic/gabaergic system, Neurotrophins and transcription factors (BDNF, TGF-β1,CREB), Inflammation, Increased vascular disease - "Vascular depression" and Oxidative and Nitrosative stress (O&NS).
Leírás
Kulcsszavak
Depression, Dementia, Pseudodementia
Forrás