This thesis addresses the pharmacotherapy of hemorrhagic shock. Hemorrhagic shock is a commonly encountered problem and most frequently caused by trauma. Lack of perfusion to vital organs causes multi organ dysfunction. Mainstay in therapy has been resuscitation with intravenous fluids and red blood cell transfusions, but complications frequently develop, especially in the setting of mass transfusions. This review sets out to address the most clinically relevant aspects of the pharmacotherapy of hemorrhagic shock.