Cardiac effect of acute hyperinsulinemia and chronic fat feeding
Absztrakt
Within cardiomyocytes, the negative effects summarised by changing insulin signaling, increasing substrate accumulation and inflexibility in metabolism shifting. All these will result in dyslipidemia, inflammatory responses, endothelial damage, lipotoxicity and activation of oxidative strett.
Leírás
Kulcsszavak
Hyperinsulinemia, Chronic fat feeding