Incretin Based Therapy of Type 2 Diabetes Mellitus

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorBjornsdottir, Hrafnhildur Greta
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptKenézy Kórház Aneszteziológiai és Intenziv Therápiás Osztályhu_HU
dc.date.accessioned2015-11-19T13:21:46Z
dc.date.available2015-11-19T13:21:46Z
dc.date.created2015
dc.description.abstractThe incidence of type 2 diabetes mellitus is increasing rapidly worldwide together with obesity. This leads to increased demand for new and improved antidiabetic medications which has led to the discovery of the incretin mimetics. The physiological incretins in the body include glucagon like peptide-1 as well as gastric inhibitory polypeptide (also known as glucose-dependent insulinotropic polypeptide), one of their main physiological action is to stimulate glucose dependent insulin secretion. These compounds get deactivated by the dipeptidyl-peptidase IV enzyme. The two classes of drugs that have been developed based on the incretin mechanism include DPP-IV inhibitors and GLP-1 analogues. Both classes of drugs have been found to be beneficial in the treatment of type 2 diabetes mellitus as well as having a relatively good safety profile.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent41hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/218614
dc.language.isoenhu_HU
dc.subjectDiabetes mellitus type 2hu_HU
dc.subjectIncretinhu_HU
dc.subjectDPP-IV inhibitorshu_HU
dc.subjectGLP-1hu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleIncretin Based Therapy of Type 2 Diabetes Mellitushu_HU
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