The effects of capsaicin compounds on some essential genes of Fusarium graminearum

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dc.contributor.advisorFazekas, Mónika Éva
dc.contributor.authorChimid, Khulan
dc.contributor.departmentDE--Mezőgazdaság- Élelmiszertudományi és Környezetgazdálkodási Kar
dc.date.accessioned2025-06-19T08:23:04Z
dc.date.available2025-06-19T08:23:04Z
dc.date.created2025-05-06
dc.description.abstractThis thesis examines the antifungal potential of capsaicin derivatives (OM94, OM97, OM103, OM106, etc.) against Fusarium graminearum, a pathogen responsible for Fusarium head blight (FHB) and mycotoxin contamination in cereals. The study targets essential fungal genes (PKS4, PKS12, Tri5, FUM1, FUM7) involved in toxin biosynthesis, using qPCR to analyse gene expression changes under capsaicin treatment. By incorporating capsaicin compounds into PDA media at varying concentrations (5–200 mg/L), the research aims to identify whether these natural compounds can suppress virulence genes or alter metabolic pathways. The work bridges gaps in understanding plant-derived antifungal agents and their molecular mechanisms against F. graminearum. If proven effective, capsaicin could offer a sustainable alternative to chemical fungicides, reducing mycotoxin risks in food chains. The thesis underscores the need for innovative strategies to combat crop diseases while minimising environmental and health impacts.
dc.description.courseFood Engineering BSc
dc.description.degreeBSc/BA
dc.format.extent41
dc.identifier.urihttps://hdl.handle.net/2437/393592
dc.language.isoen
dc.rights.infoHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectFusarium graminearum
dc.subjectCapsaicin antifungal effects
dc.subjectFusarium head blight (FHB) control
dc.subjectMycotoxin inhibition
dc.subjectPKS4 gene expression
dc.subjectTri5 gene regulation
dc.subjectPKS12 gene modulation
dc.subjectNatural antifungal agents
dc.subjectPlant pathogen resistance
dc.subject.dspaceAgricultural Sciences::Agricultural Microbiology
dc.titleThe effects of capsaicin compounds on some essential genes of Fusarium graminearum
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