The effects of Tks4 adaptor protein on the tumor microenvironment
dc.contributor.advisor | Lányi , Árpád | |
dc.contributor.advisor | Gyöngyösi , Adrienn | |
dc.contributor.author | Elsaid, Fares Amgad Elmongy Abdelatti | |
dc.contributor.department | DE--Természettudományi és Technológiai Kar--Biológiai és Ökológiai Intézet | |
dc.date.accessioned | 2024-06-10T13:37:44Z | |
dc.date.available | 2024-06-10T13:37:44Z | |
dc.date.created | 2024-05-02 | |
dc.description.abstract | According to our research, mice models lacking Tks4 exhibited slower tumor growth when injected with LLC carcinoma and B16-F10 melanoma cells. Our study also revealed that Tks4 is present in the tumor microenvironment (TME) in both high and low TAMs, as well as Mo-MDSCs populations. Moreover, we found that Tks4-dependent maturation of BM-MDSCs requires additional signals. Overall, our study provides valuable insights into the role of Tks4 in cancer and immune system regulation. | |
dc.description.course | Biology | |
dc.description.degree | BSc/BA | |
dc.format.extent | 41 | |
dc.identifier.uri | https://hdl.handle.net/2437/371308 | |
dc.language.iso | en | |
dc.rights.access | Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében. | |
dc.subject | Immunology | |
dc.subject | Molecular biology | |
dc.subject | Cell biology | |
dc.subject | Cancer cells | |
dc.subject.dspace | Biology::Immunology | |
dc.title | The effects of Tks4 adaptor protein on the tumor microenvironment |
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