Herbal medicine has been used for centuries to treat various symptoms and diseases due to its diverse components. However, the molecular mechanisms behind its effects on the human body are still largely unknown, complicating the development and application of these treatments. To address this gap, recent research is increasingly employing systems pharmacology. This approach investigates the pharmacological effects of drugs by analyzing their interaction networks. By utilizing systems pharmacology, researchers aim to better understand the complexities of how herbal medicine influences health and disease. This promising method could pave the way for more effective herbal treatments.