Synthesis of sugar-based (thio)semicarbazones as precursors of half-sandwich platinum-group metal complexes

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dc.contributor.advisorVágvölgyiné Tóth, Marietta
dc.contributor.authorHalaseh, Makram
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Kémiai Intézet
dc.date.accessioned2023-12-13T09:59:42Z
dc.date.available2023-12-13T09:59:42Z
dc.date.created2023-11-17
dc.description.abstractIn the Chemical Glycobiology Research Group (Department of Organic Chemistry, University of Debrecen) many bioactive monosaccharide derivatives have been designed and synthesized for many years. During this work, sugar containing half-sandwich platinum-group metal complexes have been synthesized and patented. Some have shown (sub)micromolar cytostatic activity against carcinoma, lymphoma and sarcoma cancer. The aim of this research work was to synthesize sugar-based semicarbazone and thiosemicarbazone derivatives as percursors of new platinum-group metal complexes.
dc.description.courseBiochemical engineering
dc.description.degreeBSc/BA
dc.format.extent31
dc.identifier.urihttps://hdl.handle.net/2437/362250
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectThiosemicarbazones
dc.subjectSemicarbazones
dc.subjectSynthesis
dc.subject4-phenyl semicarbazones
dc.subject4-phenyl thiosemicarbazones
dc.subjecthalf sandwich platinum metal complexes
dc.subject.dspaceDEENK Témalista::Kémia::Szerves kémia
dc.titleSynthesis of sugar-based (thio)semicarbazones as precursors of half-sandwich platinum-group metal complexes
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