Variety testing including disease resistance test of the major crops has been carrying out since the 1960’s in Hungary. Testing for resistance of the new candidate varieties is performed in the so-called VCU (Value for Cultivation and Use) trials under natural infection and in special small-plot or micro-plot trials using different disease provocative methods. Disease resistance, especially those of multiple and horizontal-type (race non-specific, partial or durable) resistances, has recently become a key limiting factor in the state variety registration. The role of disease resistance in the decision-making process of variety registration is demonstrated on the examples of winter wheat and sunflower as two major field crops in Hungary.