therapies to reduce LDL-cholestrol (MTP),(ACAT),sequalene synthasis inhibitor.therapies for triglycerides e.g(omega-3 fatty acids and DGAT inhibitors. therapies to raise HDL e.g:(CETP) inhibitors and PPAR-delta agonists.statin,the fibrate ,bile acid sequestrian and niacin are the most common lipid lowering agents .