Comparative test of different antimicrobial preservatives for external pharmaceutical  formulations

dc.contributor.advisor	Nemes, Dániel
dc.contributor.author	Boustanchi, Ali
dc.contributor.department	DE--Gyógyszerésztudományi Kar
dc.date.accessioned	2024-04-18T12:15:21Z
dc.date.available	2024-04-18T12:15:21Z
dc.date.created	2024-02-29
dc.description.abstract	This study explores the efficacy of antimicrobial preservatives in topical gels, following European Pharmacopoeia guidelines and Hungarian national formulary standards. Results indicate that benzoic and sorbic acid salts exhibit significant antimicrobial activity, making them promising alternatives to parabens. However, zinc gluconate and ethanolic solutions of methyl paraben showed limited efficacy. Surprisingly, the choice of gelling agent did not significantly affect the effectiveness of the tested materials. Overall, the study contributes to enhancing the safety and efficacy of external pharmaceutical formulations by addressing concerns about preservative toxicity and ensuring microbial stability throughout product shelf life.
dc.description.course	gyógyszerész
dc.description.courselang	angol
dc.description.degree	egységes, osztatlan
dc.format.extent	32
dc.identifier.uri	https://hdl.handle.net/2437/368982
dc.language.iso	en
dc.rights.access	Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subject	preservative effectiveness
dc.subject.dspace	Medicine
dc.title	Comparative test of different antimicrobial preservatives for external pharmaceutical formulations

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