Pharmacological characteristics of Ganoderma lucidum nutrients were listed up and discussed. Specific components are as follow; polysaccharides, triterpenes, cerebrosides, peptides and polyphenols. Beneficial functions of each components were listed up. Anti-proliferative, immunomodulatory, antioxidative, anti-cancer, anti-microbial and anti-insomnia effects of the mushroom were discussed. Extracts of the mushroom may function as beneficial medicine, but there are few data of the effect of Ganoderma lucidum against human.