Diabetic cardiomyopathy is the presence of a disorder in the heart muscle in people who have diabetes, which in most cases ultimately leads to heart failure. In early stages, this disease presents only with diastolic dysfunction and then later systolic dysfunction which leads to the inability of the heart to pump blood effectively. Some leading therapies of this disease are Glycemic control, Heart failure management (ABCDE), Antifibrotic and antioxidant therapies, Lifestyle modifications and emerging therapies such as stem cell and gene therapy.