Pharmacology of Current Drugs in Adjuvant Chemotherapy of Colorectal Cancer

A tétel rövid nézete
dc.contributor.advisorMegyeri, Attila
dc.contributor.advisordeptUniversity of Debrecen::Faculty of Medicine::Pharmacology and Pharmacotherapyhu_HU
dc.contributor.authorChaviv, Sivan
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentBenkő, Ilona
dc.contributor.opponentGesztelyi, Rudolf
dc.contributor.opponentdeptUniversity of Debrecen::Faculty of Medicine::Pharmacology and Pharmacotherapyhu_HU
dc.contributor.opponentdeptUniversity of Debrecen::Faculty of Pharmacy::Department of Clinical Pharmacologyhu_HU
dc.date.accessioned2014-06-22T16:10:59Z
dc.date.available2014-06-22T16:10:59Z
dc.date.created2014-03-03
dc.date.issued2014-06-22T16:10:59Z
dc.description.abstractColorectal cancer continues to be one of the most frequently diagnosed malignancies worldwide. While a curative treatment remains surgical excision, chemotherapy is an important treatment in later stages, perhaps due its elimination of micrometastases that are not readily visible during surgery (not to mention its effect on larger metastases in stage IV disease). Chemotherapeutic drugs currently approved for the use in adjuvant treatment of stage III and some cases of stage II colorectal cancer are the fluoropyrimidines 5-fluorouracil and capecitabine (with or without the addition of folinic acid, which augments their action) and the platinum analog oxaliplatin. These drugs are used in several combination therapies that increase the disease-free survival and overall survival of patients. This paper reviews the pharmacological aspects of these three chemotherapeutic agents and of folinic acid, which is a part of most regimens.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent34hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/194722
dc.language.isoenhu_HU
dc.rights.accessno_restrictionhu_HU
dc.subjectChemotherapyhu_HU
dc.subjectColorectal cancerhu_HU
dc.subject.dspaceUNL Thread List::Medicine::Pharmacologyhu_HU
dc.titlePharmacology of Current Drugs in Adjuvant Chemotherapy of Colorectal Cancerhu_HU
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Theses (Faculty of Medicine)