The role and regulation of O-GlcNAcylation in eukaryotes

A tétel rövid nézete
dc.contributor.advisorBarna, Teréz
dc.contributor.authorAliyeva, Kamilla
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biotechnológiai Intézethu_HU
dc.date.accessioned2021-05-10T04:14:51Z
dc.date.available2021-05-10T04:14:51Z
dc.date.created2021-05-07
dc.description.abstractNowadays, over 80 000 specific sites with PTMs have been discovered, including acetylation, phosphorylation, glycosylation, methylation, and ubiquitination. O-GlcNAcylation is a special case of O-linked glycosylation, which is a reversible post-translational modification that regulates the function of numerous cytosolic and nuclear proteins depending on the energy, nutrition and stress status of the cell. O-GlcNAcylation is involved in many biological processes, like transcription, translation, metabolism, signal transduction, embryogenesis, and epigenetics. In this work, my objective was to review the main characteristics of this PTM focusing on the O-GlcNAcylation pathway itself, the enzymes catalyzing the process, the connected diseases, and its role in the biology of eukaryotes.hu_HU
dc.description.courseBiochemical Engineeringhu_HU
dc.description.degreeBSc/BAhu_HU
dc.format.extent33hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/309107
dc.language.isoenhu_HU
dc.subjectO-GlcNAcylationhu_HU
dc.subjectOGThu_HU
dc.subjectOGAhu_HU
dc.subject.dspaceDEENK Témalista::Biológiai tudományokhu_HU
dc.titleThe role and regulation of O-GlcNAcylation in eukaryoteshu_HU
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