Recent improvements in diagnosis techniques, increasing knowledge of changes in cardiac metabolism and the impact of electrolyte disturbance on the formation of arrhythmias, and the understandings of the pharmacological properties of both new and old antiarrhythmic drugs have all contributed to significant advancements in the pharmacological field and clinical practice of antiarrhythmic drugs. Some of these new medications have been found to be less harmful than conventional antiarrhythmic medications and to reduce the incidence of recurring arrhythmias. In this paper, we will go through the most common antiarrhythmic drugs used today, their mechanism of action, administration route, and adverse and toxic consequences.