Management of neuromuscular blockade in paediatric patients

Abstract

This thesis highlights the history of anaesthesia, the challenges anaesthesiologists face, and the current guidelines for the management of NMBAs in paediatric patients. Emphasising the pharmacokinetic and pharmacodynamic differences between adult and paediatric patients. It also discusses commonly used NMBAs. It reviews the role of neuromuscular monitoring techniques, including acceleromyograph and electromyography, in minimising residual neuromuscular blockade. Additionally, the thesis explores the evolving role of reversal agents, such as sugammadex, compared to the regularly used anticholinesterases