Sepsis is a common life-threatening condition characterised by organ dysfunction caused by dysregulated host immune response to infection. For patients with sepsis and septic shock therapeutic priorities include securing the airway, correcting hypoxia, establish vascular access to obtain blood for routine laboratory studies, serum lactate, arterial blood gases and blood cultures. As well as cultures for easily accessible sites and imaging of suspected sites of infection sources. It is of the utmost importance that the aforementioned procedures are performed as swiftly as possible and should not delay the administration of fluids and antibiotics. The 2021 SSC guidelines suggest initial resuscitation with crystalloid fluids 30 mL/kg and IV administration of empiric broad spectrum antibiotics within the first hour of recognition. Vasopressors, preferably norepinephrine, should be administered if hypotension persist despite adequate fluid resuscitation and target mean arterial pressure of 65 mmHg is recommended.