Reactions of N-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl-carbonyl)-N’-tosylhydrazine with N-, O-nucleophiles

A tétel rövid nézete
dc.contributor.advisorJuhasné Tóth , Éva
dc.contributor.authorMudau, Zwivhuya Phoebe
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Kémiai Intézet
dc.date.accessioned2022-11-18T08:53:57Z
dc.date.available2022-11-18T08:53:57Z
dc.date.created2022-11-18
dc.description.abstractAt the Chemical Glycobiology Research Group, systematic research has been going on for many years to study the reactivity of C-glycopyranosyl-formaldehyde-tosylhydrazones. In continuation of this topic, the aim of this paper was to synthesize N-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosylcarbonyl)-N'-tosylhydrazine and to study their reactions with different N- and O-nucleophiles. The molecule was reacted in the presence of N-bromosuccinimide with several primary and secondary amines giving the desired N-substituted C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamide derivatives with low to excellent yields (5-86%). We also extended the reaction with several O- nucleophiles however, the C-glucopyranosyl-formamides and formicacid ester type molecules could not be isolated in the case of these nucleophiles.
dc.description.courseChemical Engineering
dc.description.degreeBSc/BA
dc.format.extent23
dc.identifier.urihttps://hdl.handle.net/2437/340996
dc.language.isoen
dc.subjectC-glycopyranosyl-formaldehyde-tosylhydrazones.
dc.subjectCarbohydrates
dc.subjectN- and O-nucleophiles
dc.subject.dspaceDEENK Témalista::Kémia
dc.titleReactions of N-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl-carbonyl)-N’-tosylhydrazine with N-, O-nucleophiles
Fájlok
Gyűjtemények
Theses (Faculty of Science and Technology)