Sudden cardiac death is an unexpected natural death, usually of cardiac origin, preceded by abrupt loss of consciousness within one hour of the onset of the acute symptoms. Cardiac causes account for 80% of the deaths, while non-cardiac causes are about 20%. Prevention of sudden cardiac death has implications to public health. According to the National Center for Health Statistics, heart disease is the first cause of death in the United States, because more than 600,000 deaths are attributed to heart disease per year, and half of it is estimated to be sudden. Half of the sudden cardiac deaths are the first recognized cardiac events, and only a few will survive of those who suffer cardiac arrest out of hospital. According to the Hungarian National Heart Foundation, there are 26,000 people a year, so 70 people a day, who die of SCD in Hungary. Sudden cardiac death can be caused by multiple factors, such as, certain inheritable heart diseases, coronary diseases or arrhythmya, but most of the time we cannot find the cause, it can also be caused by stress and physical exertion. Sudden cardiac death is a high priority public health problem, treatment and prevention are necessary to approach based on various criteria. This thesis contains epidemiology, incidence of sudden cardiac death and cardiac arrest in chronic kidney disease. Deals with the risk factors: cardiomyopathy, ischemic heart disease, QT dispersion, electrolyte shifts, inflammation and other risk factors. It is important to prevent such a high priority disease, so the thesis deals with coronary ischemic markers, electrocardiography, left ventricular hypertrophy, heart rate variability and baroreceptor sensitivity. Pharmacological treatment and dose of dialysis are equally important for the prevention, the use of defibrillators can save the patients lifes.