Comparing levels of heterozygosity and Loss-of-Heterozygosity regions in baker’s yeasts

A tétel rövid nézete
dc.contributor.advisorPfliegler, Valter Péter
dc.contributor.authorDlamini, Zamasiba Phakama
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biológiai és Ökológiai Intézethu_HU
dc.date.accessioned2021-04-29T20:55:33Z
dc.date.available2021-04-29T20:55:33Z
dc.date.created2021
dc.description.abstractThis thesis covers the genotype analysis of baker's yeastusing analysis tools such as GATK, Picard, and Galaxy project. We looked at the levels of heterozygosity and Loss of Heterozygosity (LOH) among four baker's yeast strains. We looked at the ploidy of the different yeast strains to determine the genetic instability within the genomes. The chromosomes in all four strains of Baker's yeast were shown to be tetraploid, with very few monosomic, disomic, or trisomic regions. In comparison to tetraploid yeasts, diploid yeasts have higher gene instability. This indicates the tetraploids became more stable due to the presence of more genetic mutations, resulting in an improvement in adaptability.hu_HU
dc.description.courseBiochemical Engineeringhu_HU
dc.description.degreeBSc/BAhu_HU
dc.format.extent40hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/307854
dc.language.isoenhu_HU
dc.subjectBaker's yeasthu_HU
dc.subjectHeterozygosityhu_HU
dc.subjectLoss of Heterozygosity (LOH)hu_HU
dc.subjectGATKhu_HU
dc.subjectFermentationhu_HU
dc.subjectgenotype analysishu_HU
dc.subject.dspaceDEENK Témalista::Biológiai tudományokhu_HU
dc.titleComparing levels of heterozygosity and Loss-of-Heterozygosity regions in baker’s yeastshu_HU
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