Formulation of Nanoparticles Containing Casein Kinase 2 Inhibitor for the Therapy of Glioblastoma

Dátum
Folyóirat címe
Folyóirat ISSN
Kötet címe (évfolyam száma)
Kiadó
Absztrakt

Glioblastoma is the most prevalent and aggressive type of brain cancer accounting for 15% of all primary brain tumours. A lack of curative treatment options, coupled with its invasive nature and resistance to treatment means about 90% of patients die within 5 years of diagnosis. Identified as a possible treatment option, Casein Kinase 2 inhibitors have shown promise as a potent curative option for the disease. Combining a solution containing the inhibitor with a suitable polymer causes formation of nanoparticles that encapsulate the inhibitor. These nanoparticles can then be injected directly into the brain to target the glioblastoma cells.

Leírás
Kulcsszavak
nanoparticles, glioblastoma, cancer
Forrás