This medical thesis provides a comprehensive analysis of Trigeminal Neuralgia, a debilitating condition characterized by intense, paroxysmal facial pain. The author explores the neuroanatomical foundations of the trigeminal nerve and details how current classification systems differentiate between classical, secondary, and idiopathic subtypes. A significant portion of the text evaluates pharmacological strategies, identifying This medical thesis offers a detailed analysis of Trigeminal Neuralgia, a disabling condition marked by intense, sudden facial pain. The author discusses the neuroanatomy of the trigeminal nerve and explains how current classification systems distinguish between classical, secondary, and idiopathic subtypes. A large part of the study evaluates drug treatments, highlighting carbamazepine and oxcarbazepine as the main first-line options while exploring new molecular therapies and anticonvulsants. Besides medication, the paper reviews surgical procedures such as microvascular decompression and various percutaneous methods for patients with treatment-resistant symptoms. Ultimately, the work promotes a multidisciplinary approach to treatment, stressing the importance of personalized care to enhance the long-term quality of life for those affected by this chronic nerve disorder.carbamazepine and oxcarbazepine as the primary first-line treatments while examining emerging molecular therapies and anticonvulsants. Beyond medication, the document assesses surgical interventions like microvascular decompression and various percutaneous procedures for patients with treatment-resistant symptoms. Ultimately, the work advocates for a multidisciplinary approach to management, emphasizing the need for personalized care to improve the long-term quality of life for those suffering from this chronic neuropathic disorder.