Pharmacology and Therapeutic Potential of N,N-Dimethyltryptamine: Ischemia-Related Application
dc.contributor.advisor | Gyöngyösi , Alexandra | |
dc.contributor.advisordept | Gyógyszerésztudományi Kar::Gyógyszerhatástani Tanszék | |
dc.contributor.author | Aghapour Olilo, Benyamin | |
dc.contributor.department | DE--Gyógyszerésztudományi Kar | |
dc.contributor.opponent | Bak , István | |
dc.contributor.opponent | Vasvári , Gábor | |
dc.date.accessioned | 2025-04-11T09:04:02Z | |
dc.date.available | 2025-04-11T09:04:02Z | |
dc.date.created | 2025-04-10 | |
dc.description.abstract | This thesis explores the therapeutic potential of N,N-Dimethyltryptamine (DMT), a naturally occurring psychedelic compound known for its intense but short-lasting psychoactive effects. Recent preclinical and clinical studies suggest that DMT may have neuroprotective, anti-inflammatory, and psychological healing properties, particularly in conditions like treatment-resistant depression, anxiety, and PTSD. Unlike other psychedelics, DMT also exhibits rapid onset and short duration, making it a promising candidate for controlled clinical use with minimal time burden. The thesis also examines DMT’s interactions with sigma-1 receptors, which play a key role in cellular stress response and neuroregeneration. Ethical, regulatory, and pharmacological considerations are discussed to evaluate its future integration into modern psychiatric and neurological therapy. Overall, DMT emerges as a high-potential molecule that warrants further clinical investigation for its role in next-generation therapeutics. | |
dc.description.course | gyógyszerész | |
dc.description.courselang | angol | |
dc.description.degree | egységes, osztatlan | |
dc.format.extent | 30 | |
dc.identifier.uri | https://hdl.handle.net/2437/389018 | |
dc.language.iso | en | |
dc.rights.info | Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében. | |
dc.subject | DMT | |
dc.subject | N,N-Dimethyltryptamine | |
dc.subject | Ischemia-Reperfusion Injury | |
dc.subject | Psychedelics | |
dc.subject.dspace | Medicine::Pharmacology | |
dc.title | Pharmacology and Therapeutic Potential of N,N-Dimethyltryptamine: Ischemia-Related Application |
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