Current treatment of Ulcerative Colitis

Abstract

This thesis reviews the available treatment options for ulcerative colitis, focusing on their mechanisms of action, efficacy, and safety profiles. It discusses conventional therapies, including 5-aminosalicylates, corticosteroids, and immunomodulators, alongside newer treatments such as biologics, JAK inhibitors, and S1P receptor modulators. The thesis highlights recent advances in pharmacological management and the growing importance of individualized treatment strategies to achieve sustained remission, minimize adverse effects, and improve patients’ quality of life.