Hypopituitarism is a partial or complete deficiency of pituitary hormones. Hypopituitarism manifests in many forms, depending on the hormone that was lost and to what extent. We should treat hypopituitarism to restore the physiological hormonal activity in the body, to help the patient regain as much as they can from their daily normal functioning and improve their quality of life. In this thesis I discuss the different treatment options and their efficiency.