Mechanisms and pharmacotherapies of arrhythmia

Abstract

Arrhythmias are a cluster of diseases characterized by the abnormality in the cardiac rhythm. The myocardium is an electrically heterogeneous tissue and a regional expression of ion channels, regulating excitability, is primarily responsible for setting up the normal pace of the heart. The pharmacotherapy of arrhythmias is correspondently undeniably complex, and mistakes in diagnosis and the initiation of therapy could potentially lead to fatal outcomes.