Assessment of cellular uptake and endosomal release of a cell-penetrating peptide in Mus musculus liver tissue

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dc.contributor.advisorBatta, Gyula
dc.contributor.authorNguyen, Hai Dang
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biológiai és Ökológiai Intézet
dc.date.accessioned2023-12-12T12:37:59Z
dc.date.available2023-12-12T12:37:59Z
dc.date.created2023-11-15
dc.description.abstractThe selective permeability of the lipid bilayer poses an enormous challenge to intracellularly active drugs. Here we investigate the ability of a cell-penetrating peptide (CPP) to traverse the plasma membrane in Mus musculus liver tissue. The study employs a range of biophysics methods including fluorescence microscopy and fluorescence spectroscopy. By elucidating the properties of the CPP, we hope to assess its potential as a therapeutic molecule carrier in future studies in pharmacology.
dc.description.courseBiology
dc.description.degreeBSc/BA
dc.format.extent34
dc.identifier.urihttps://hdl.handle.net/2437/362187
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectCell-penetrating peptide
dc.subjectBiophysics
dc.subjectFluorescence microscopy
dc.subject.dspaceDEENK Témalista::Biológiai tudományok
dc.titleAssessment of cellular uptake and endosomal release of a cell-penetrating peptide in Mus musculus liver tissue
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