Synthesis and characterization of a Mn(II)-based Magnetic Resonance Imaging(MRI) contrast agent candidate derived from pyclen

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dc.contributor.advisorGyula, Tircsó
dc.contributor.advisorIstván, Kapus
dc.contributor.authorAnsari , Arman Ahmad
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Kémiai Intézet
dc.date.accessioned2024-06-06T13:00:06Z
dc.date.available2024-06-06T13:00:06Z
dc.date.created2024-05-03
dc.description.abstractMRI is one of the best-known and most widely used imaging techniques in modern medicine, and its popularity is due to its non-invasive and non-destructive features. Since the 1980s, Gd(III)-based contrast agents have been market leaders, but in recent years, confidence has been shaken by the toxicity of the released gadolinium(III) ions. The essential nature of metal ions is applied to replace Gd(III)-ions in most cases (represented by Mn2+). For manganese complexation, the ligand O2PC6OX was designed and synthesized, and its Mn(II) complex was investigated in order to evaluate its thermodynamic, kinetic, and relaxometric features, with the goal of obtaining a Mn(II) complex with improved physico-chemical parameters.
dc.description.courseChemistry MSc
dc.description.degreeMSc/MA
dc.format.extent40
dc.identifier.urihttps://hdl.handle.net/2437/371062
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectMagnetic Resonance Imaging, Contrast Agent, Pyclen, Manganese, 8-hydroxyquinoline, ligand
dc.subject.dspaceChemistry
dc.titleSynthesis and characterization of a Mn(II)-based Magnetic Resonance Imaging(MRI) contrast agent candidate derived from pyclen
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