Treatment of metastatic renal cancers

A tétel rövid nézete
dc.contributor.advisorBerczi, Csaba
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Urológiai Klinikahu_HU
dc.contributor.authorLevy, Adam
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentJuhász, Balázs
dc.contributor.opponentMurányi, Mihály
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Onkológiai Intézethu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Urológiai Klinikahu_HU
dc.date.accessioned2017-08-02T09:00:01Z
dc.date.available2017-08-02T09:00:01Z
dc.date.created2017
dc.description.abstractRenal cancer represents approximately 3 % of total malignancies. Based on the statistics distant metastasis is present at least 30% of renal cancers at the time of diagnosis. The metastatic renal tumors have an extremely high rate of mortality and poor survival. The conventional chemotherapy was not effective for the treatment of metastatic renal carcinomas. However, in the past decade the administration of different targeted therapies improved the survival of metastatic renal cell carcinomas. At present we use antivascular endothelial growth factor receptor (VEGFR) inhibitor, tyrosine kinase inhibitors (TKIs) and mammalian target of rapamycin (mTOR) inhibitors in the adjuvant setting for metastatic renal tumors. Due to the administration of the targeted therapies the outcome of this population improved, but, despite the partly prolonged survival, the majority of patients will develop resistance to targeted therapies.hu_HU
dc.description.correctortben
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent41hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/242788
dc.language.isoenhu_HU
dc.subjectrenalhu_HU
dc.subjectcancer
dc.subjecttreatment
dc.subject.dspaceDEENK Témalista::Orvostudomány::Urológiahu_HU
dc.titleTreatment of metastatic renal cancershu_HU
dc.title.translatedMetasztatikus vese-rák kezelésehu_HU
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