Domino Knoevenagel-cyclization reactions for the preparation of pyridine-containing condensed heterocycles

A tétel rövid nézete
dc.contributor.advisorSándor, Király
dc.contributor.authorAnjou, Tarek
dc.contributor.authorKurtán, Tibor
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biotechnológiai Intézet
dc.date.accessioned2022-11-11T10:27:27Z
dc.date.available2022-11-11T10:27:27Z
dc.date.created2022-11-10
dc.description.abstractIn this thesis work, the goal was to synthesize chiral condensed O,N-heterocycles by the domino Knoevenagel-hetero Diels-Alder reaction from a 2-H-chromene derivative containing a pyridine-3-carbaldehyde moiety as a starting material. Eight new condensed chiral O,N-heterocycles were successfully synthesized and analyzed by NMR, no other ring closure mechanism was observed in these reactions. The synthesized compounds are to be studied in anti-proliferative activity assays against various cancer cell lines to compare activity with the previously synthesized benzenecondensed analogues.
dc.description.courseBiochemical Engineering
dc.description.degreeBSc/BA
dc.format.extent33
dc.identifier.urihttps://hdl.handle.net/2437/339476
dc.language.isoen
dc.subjectHeterocycles
dc.subjectDomino reactions
dc.subjectAntiproliferative
dc.subject.dspaceDEENK Témalista::Kémia::Szerves kémia
dc.titleDomino Knoevenagel-cyclization reactions for the preparation of pyridine-containing condensed heterocycles
Fájlok
Gyűjtemények
Theses (Faculty of Science and Technology)