Modern therapeutics in rheumatoid arthritis and spondyloarthritis

A tétel rövid nézete
dc.contributor.advisorSzekanecz, Zoltán
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Belgyógyászati Intézet::Reumatológiai Tanszékhu_HU
dc.contributor.authorBjörnsson, Aron Hjalti
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentSzűcs, Gabriella
dc.contributor.opponentGáspár, Krisztián
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Belgyógyászati Intézet::Reumatológiai Tanszékhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Bőrgyógyászati Klinikahu_HU
dc.date.accessioned2018-01-19T11:15:06Z
dc.date.available2018-01-19T11:15:06Z
dc.date.created2017-05-30
dc.description.abstractTwo decades ago, the introduction of the TNF inhibitors revolutionised the treatment of rheumatoid arthritis and spondyloarthritis. In the years to follow, more targeted therapies where introduced for rheumatoid arthritis. However, there has been an unmet need of an oral agent, with comparable efficacy as the biologics. Further, few alternative biologics have been available for patients with spondyloarthritis. In this review thesis, the biologic agents used to date, the new therapeutic agents targeting the IL-23/IL-17 axis and the Janus kinase, and their molecular background will be discussed.hu_HU
dc.description.correctorVÁSZ
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent51hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/247217
dc.language.isoenhu_HU
dc.subjectRheumatologyhu_HU
dc.subjectArthritishu_HU
dc.subjectRAhu_HU
dc.subjectSpondyloarthritishu_HU
dc.subjectTNF inhibitorshu_HU
dc.subjectTNF blockershu_HU
dc.subjectBiologicshu_HU
dc.subjectSmall molecule drugshu_HU
dc.subjectPsoriasis arthritishu_HU
dc.subjectRheumatoid arthitishu_HU
dc.subjectUstekinumabhu_HU
dc.subjectSecukinumabhu_HU
dc.subjectBrodalumabhu_HU
dc.subjectIxekizumabhu_HU
dc.subjectTofacitinibhu_HU
dc.subjectBaricitinibhu_HU
dc.subjectinfliximabhu_HU
dc.subjectetanercepthu_HU
dc.subjectadalimumabhu_HU
dc.subjectcertolizumab pegolhu_HU
dc.subjectcertolizumabhu_HU
dc.subjectgolimumabhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleModern therapeutics in rheumatoid arthritis and spondyloarthritishu_HU
dc.title.subtitleThe IL23/IL17 axis and small molecular therapyhu_HU
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Gyűjtemények
Theses (Faculty of Medicine)