Szerző szerinti böngészés "Ranga, Madalina"
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Tétel Korlátozottan hozzáférhető Adsorption of bovine serum albumin on silica aerogel surface: Detailed kinetic model of the systemRanga, Madalina; Forgács, Attila; DE--Természettudományi és Technológiai Kar--Kémiai IntézetIn this thesis, I investigated the interaction of bovine serum albumin (BSA) and mesoporous silica aerogel, which can be used as a potential drug carrier and tissue scaffold in the biomedical field. Since bovine serum albumin is similar to human serum albumin (HSA), it is suitable for modeling the aerogel-protein system.During the experiments, BSA adsorption was observed on the mesoporous silica surface, which was confirmed by light microscopic examinations. The obtained UV-vis kinetic data were corrected using the Dual-Wavelength Method of background correction, to eliminate the background caused by the turbidity of the aerogel suspension. The results suggest that a complex process occurs after the injection of BSA solution into the aerogel suspension.Tétel Szabadon hozzáférhető Interaction of Aqueous Bovine Serum Albumin with Silica Aerogel Microparticles: Sorption Induced Aggregation(2022) Forgács, Attila; Ranga, Madalina; Fábián, István; Kalmár, JózsefTétel Korlátozottan hozzáférhető Synthesis and characterization of gelatin, and crosslinked gelatin aerogelsRanga, Madalina; Forgács, Attila; DE--Természettudományi és Technológiai Kar--Kémiai IntézetThis research aims to characterize newly synthesized pure high gelatin content aerogels and the crosslinked version of the gelatin aerogels with glutaraldehyde (GTA). The cross-linking process was achieved by the interaction of the gelatin gel with the crosslinker (GTA) and using a subsequent supercritical CO2 drying process. Three different aerogels with the following composition will be studied: 30 wt.% gelatin/water (RM01); 20 wt.% gelatin/water (RM04); and 20 wt.% gelatin/water crosslinked with 2.5 wt. % GTA (RM06). In this research, the focus is the characterization of newly synthesized advanced materials by conventional characterization techniques (SEM, N2-porosimetry, IR) as well as compressive strength tests. The SEM pictures illustrate the dense fibrils-like structure of the pure gelatin samples and the altered one of the GTA-gelatin crosslinked, impacting the strength of the two types of aerogels. Moreover, with increasing gelatin content we can observe a trend in increasing the mechanical properties which give these materials the ability to withstand high stress.