Beta-blockers are important group of drugs that is particularly used for treatment, prevention and management of the cardiovascular diseases. Determination and controlling these patients who visit the dental clinic are given significant information to dentists and surgeons, especially in the medicine uptake. So, it's improtant to know the current medical problems of each patients and which generation of the beta-blockers they can take. Dentists can examine carefully the oral manifestation of the patients if they are able to have beta-blocker therapy for long time because of misdiagnosis. In addition, dentists and dental surgeons must be able to identify medical emergencies and adopt the measures to avoid them and treat them quickly and effectively.