Pathomechanism, diagnosis and surgical management of Crohn's disease

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Crohn’s disease, a chronic inflammatory bowel disease with a relapsing-remitting course, has become an increasing burden in recent years and the incidence and prevalence of this idiopathic disease is continually escalating worldwide. While Crohn’s disease is currently incurable, the diagnosis, management and prognosis for patients have considerably improved. According to the institute’s statistics program which was used to analyzed 173 surgeries between 2011 and 2017, it was evident that the most common surgical interventions performed were small bowel and ileocecal resections as the inflammation in Crohn’s disease has a predilection for the small intestines, particularly the ileum, and the cecum. Regarding the post-operative complications, the most prevalent was intra-abdominal sepsis and peritonitis. It can be concluded that the data from the Department of Surgery at the University of Debrecen matched the international standards regarding the most common surgical procedures performed whereas the post-operative complication rate and surgical mortality rate were lower than the international standards.

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Crohn's disease, surgical management, Pathophysiology, diagnosis
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