The study aims to examine the effects of palm biodiesel blended with additives in the compression ignition (CI) engine. Biodiesel as fuel was limited by challenges such as lower calorific value (CV) and higher viscosity while increasing brake specific fuel consumption (BSFC) and nitrogen oxides (NOx) emissions. Nanoparticles and antioxidant additives added to biodiesel play an essential role in avoiding the hindrances of biodiesel. The antioxidants combined with biodiesel reduced NOx emissions by eliminating decomposing peroxides, free radicals, and preventing free radicals' chain reaction. The Significant characteristics of nanoparticles are high CV, high thermal conductivity, and higher surface to volume ratio. These characteristics are used to improve the CI engine's performance and emissions by using nanoparticles blended with biodiesel. Five different test blends of Diesel, B20, B20TO, B20AO, and B20AOTO were prepared. The result showed high brake thermal efficiency (BTHE) and decreased BSFC, exhaust gas temperature (EGT), hydrocarbons (HC), NOx, and HC emissions by using the B20AOTO fuel blend contrasted with other biodiesel blends.