Innovative Therapies in the Treatment of Melanoma

dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorTang, Ching-Fang
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentMegyeri, Attila
dc.contributor.opponentdeptKenézy Kórház, Központi Aneszteziológiai és Intezív Terápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2021-09-16T11:34:35Z
dc.date.available2021-09-16T11:34:35Z
dc.date.created2021-04
dc.description.abstractPrior to the advances in melanoma treatment options, conventional therapeutic modalities including chemotherapy and interleukin-2 remained the mainstay in the treatment of advanced-stage melanoma. They demonstrate low clinical efficacies and minimal durable responses. In recent years, significant breakthrough has been made in the field of melanoma treatment. The discovery of immune checkpoint inhibitors has led to a new era in cancer immunotherapy. In addition, with extensive researches in the molecular background of melanoma, the field of targeted therapies also began to prosper. The introduction of innovative agents has greatly improved the clinical outcome of patients with advanced melanoma, with immune checkpoint inhibitors providing a durable long-term remission while targeted therapies delivering faster responses. Moreover, with numerous researches and clinical trials now investigating new therapeutic strategies such as newer combination therapies, cancer vaccines, and nanotechnology, we expect to see more advancements in the treatment modalities for this deadly disease in the upcoming future.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent56hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/321809
dc.language.isoenhu_HU
dc.subjectmelanomahu_HU
dc.subjecttumor immunologyhu_HU
dc.subjectimmunotherapyhu_HU
dc.subjectimmune checkpoint inhibitorhu_HU
dc.subjecttargeted therapyhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleInnovative Therapies in the Treatment of Melanomahu_HU
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