Comparison of endotoxin levels in cow’s milk samples derived from farms and shops

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dc.contributor.authorSipka, Sándor
dc.contributor.authorBéres, Andrea
dc.contributor.authorBertók, Lóránd
dc.contributor.authorVarga, Tamara
dc.contributor.authorBruckner, Geza
dc.contributor.authorSipka Sándor (1945-) (immunológus, laboratóriumi hematológus)
dc.contributor.submitterdepBelgyógyászati Intézet -- 84
dc.contributor.submitterdepKlinikai Immunológiai Tanszék -- 60
dc.contributor.submitterdepÁOK
dc.contributor.submitterdepDebreceni Egyetem
dc.date.accessioned2019-01-09T10:49:41Z
dc.date.available2019-01-09T10:49:41Z
dc.date.oa2019-03-06
dc.date.updated2019-01-09T10:49:41Z
dc.description.abstractThe observations on the protective effect of bacterial endotoxin in farm-derived cow’s milk on childhood asthma and allergy are contradictory. The aim of this study was to determine the endotoxin levels in ‘farm-derived whole raw’ and ‘processed shop’ sources of cow’s milk, and to test how the temperature and storing conditions might alter their endotoxin concentrations. Milk was collected from farms and shops. The level of endotoxin was measured by micro (gel-clot) Limulus amebocyte lysate test expressed as EU/ml. The concentration ranges of endotoxin were much higher and more widely scattered in the samples of whole raw farm milk than in the processed shop milk. Cold storage or heating increased the endotoxin concentrations in all samples of farm milk, but not in the processed shop milk. These results show that elevated levels of endotoxin in raw farm milk samples can occur from the cowshed or be formed during storage. In processed shop milk, storage does not cause any changes in the amount of endotoxin. Therefore, it is consistent that the handling and storage of raw milk alters the endotoxin concentrations, which may explain previous contradictory findings regarding the beneficial modulating effects on innate immunity toward allergy prevention in early childhood.
dc.description.correctorLB
dc.identifier.citationInnate Immunity. -21 : 5 (2015), p. 531–536. -Innate Immun. -1753-4259. -1753-4267
dc.identifier.doi10.1177/1753425914557100
dc.identifier.issn1753-4259. -
dc.identifier.issn1753-4267
dc.identifier.opachttp://webpac.lib.unideb.hu:8082/ebib/CorvinaWeb?action=cclfind&resultview=long&ccltext=idno+BIBFORM076593
dc.identifier.urihttp://hdl.handle.net/2437/262904
dc.identifier.urlhttps://journals.sagepub.com/doi/10.1177/1753425914557100
dc.languageeng
dc.rights.accessopen access journal
dc.rights.ownerszerző
dc.subject.otheridegen nyelvű folyóiratközlemény külföldi lapban
dc.subject.otherAllergy prevention, cow’s milk
dc.subject.otherendotoxin
dc.subject.othertemperature dependence
dc.titleComparison of endotoxin levels in cow’s milk samples derived from farms and shops
dc.typefolyóiratcikk
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